Hyaluronic NIACIN

Most acne treatments focus on killing bacteria or drying oil without understanding that healthy skin microbiome is essential for acne prevention and long-term skin resilience. Mixlab Hyaluronic Niacin is fundamentally different because it addresses the root cause: microbiome imbalance. Niacinamide is one of the most widely studied topical skincare ingredients with clinically documented efficacy across multiple acne mechanisms. At 5% clinical concentration, Niacinamide rebalances the skin's microbiome — it supports beneficial bacteria whilst reducing C. acnes (the acne-causing bacterium) overgrowth. This is different from conventional acne treatments that indiscriminately kill all bacteria, which actually damages the microbiome and worsens long-term acne. Beyond microbiome balancing, Niacinamide reduces acne and blemishes, decreases redness and inflammation, reduces post-acne pigmentation, balances tone, and increases hydration. As a precursor in cellular energy coenzymes (NAD and NADP), it supports optimal cellular function — acne skin is metabolically stressed skin. The Swiss-sourced, extra-purified formulation ensures clinical efficacy. XS hyaluronic acid provides hydration support (acne skin is often dehydrated, worsening inflammation). The fruit acid blend provides gentle micro-exfoliation without disrupting the microbiome. Most acne treatments are destructive; this one is restorative.

Yes — Niacinamide is exceptionally well-tolerated, even by reactive skin. Unlike harsh acne treatments that strip and irritate, Niacinamide supports barrier function and reduces inflammation whilst addressing acne. The fruit acid blend is gentler than conventional acne exfoliants. The hyaluronic acid provides calming hydration. For sensitive acne-prone skin, use morning and evening consistently — the gentle, restorative mechanism means you get acne control without irritation or sensitivity escalation. Clients with reactive acne-prone skin often report that Niacinamide improves overall skin resilience, not just clears acne.

This is your microbiome-balancing and acne-fighting serum step, used morning and evening as foundational infrastructure. Morning routine: cleanse → apply Hyaluronic Niacin to clean skin → allow to absorb fully (2–3 minutes) → apply other serums or treatments if using → apply moisturiser → SPF 50+. Evening routine: cleanse → apply Hyaluronic Niacin → allow to absorb → apply other treatments or night cream if desired. Hyaluronic Niacin is the foundation acne-treatment step for acne-prone skin. For Mixlab system users, this is the microbiome-balancing base layer to which personalised serums are added — apply this first (allow to absorb), then layer other Mixlab serums on top according to individual needs.

Clean skin prior to application. Apply a few drops to the skin morning and evening. Gently pat or press (do not drag) the serum into the skin, allowing it to absorb fully (2–3 minutes). A moisturiser can be applied over the top. Always apply SPF 50+ during the daytime. For Mixlab blending: apply Hyaluronic Niacin as the microbiome-balancing and acne-fighting layer, then layer other Mixlab serums on top according to personalised protocol, allowing each to absorb before applying the next. Once opened, use within 6 months.

Immediate results on first use — skin feels calmer, more hydrated, and less inflamed from Niacinamide's anti-inflammatory effects. Cumulative visible results compound over 1–3 weeks: active breakouts decrease noticeably, redness and inflammation reduce, new blemishes appear less frequently, skin tone becomes more even, and post-acne pigmentation fades. Unlike harsh acne treatments that cause visible peeling and irritation, Hyaluronic Niacin delivers results without disruption. Clients report noticeable breakout reduction and inflammation decrease within 1–2 weeks, with significant improvement in overall acne control and post-acne pigmentation by 3–4 weeks. Microbiome rebalancing continues over 6–8 weeks, with progressive improvement in skin resilience and reduced acne flare frequency.

Yes — Mixlab Hyaluronic Niacin is a topical serum with no systemic actives, making it safe during pregnancy and breastfeeding. Niacinamide is not systemically absorbed. For pregnant clients experiencing hormonal acne (common during pregnancy), this microbiome-balancing serum is ideal. The gentle, restorative approach is especially valuable during pregnancy when hormonal changes increase acne risk. The anti-inflammatory and microbiome-supporting benefits are particularly beneficial during this sensitive period.

Both. As a standalone serum, it delivers comprehensive microbiome-balancing and acne-fighting benefits and is perfect for clients seeking core acne control without harsh treatments. As part of a routine with other serums: apply Hyaluronic Niacin first (as the microbiome-balancing foundation), allow it to absorb (2–3 minutes), then layer other serums on top. The Niacinamide and hyaluronic acid infrastructure allows other actives to work optimally without irritating acne-prone skin. For Mixlab system users specifically, Hyaluronic Niacin is designed to be mixed with other Mixlab serums to create fully customised formulations — you can blend this with anti-inflammatory, brightening, or oil-control serums to create personalised, targeted formulations tailored to individual acne and skin concerns, all with microbiome-restoration foundation.

At twice-daily application (morning and evening, a few drops), a 70ml bottle lasts approximately 6–8 weeks. The lightweight serum formulation means a small amount covers the entire face and neck effectively — you need less product than heavier acne creams. The generous 70ml size provides excellent value and longevity for daily acne control use. Once opened, use within 6 months.

The value case is multifaceted and evidence-based. Most acne treatments cost less but come with harsh side effects (irritation, drying, barrier damage, microbiome destruction) that cause long-term skin problems. Mixlab Hyaluronic Niacin is premium-priced because Niacinamide is clinically documented to address acne through multiple mechanisms whilst actually supporting skin health and microbiome resilience. This is not a destructive acne treatment; it's a restorative one. Over 6–8 weeks of consistent daily use, you're seeing measurable acne reduction, inflammation decrease, post-acne pigmentation fading, and improved skin resilience — without irritation or tolerance-building. The Swiss-sourced, extra-purified Niacinamide ensures clinical efficacy and purity. For clients seeking genuine acne control without damaging their skin long-term, this is the investment that works. For Mixlab system users, this becomes the microbiome-balancing foundation to which personalised actives are added. The documented microbiome-restoration and acne-control benefits justify the investment entirely.

Aqua (Water), Niacinamide, Sodium Hyaluronate, Lactic Acid, Propanediol, Citric Acid, Tartaric Acid, Gluconic Acid, Polysorbate 80, Sodium Benzoate, Sodium Dehydroacetate, Parfum, Citral, Limonene