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Ekseption

Hyaluronic ZnPCA

Sebum-regulating serum with Zinc PCA. Reduces oily skin, acne, and rosacea.

  • Zinc PCA Sebum Regulation & Hormone Balance
  • Anti-Inflammatory & Antibacterial Action
  • Mixlab Customisable Serum System
$45.95
Size: 30 mL
  • Selected by Dr Tina Roche, Nurse Practitioner
  • Free shipping over $150 · Order by 1pm weekdays for same-day dispatch
  • 30-day returns, even if opened. Conditions apply
Hyaluronic ZnPCA 30 mL · $45.95

From your Nurse Practitioner

Why I recommend it.

Mixlab Hyaluronic ZnPCA addresses the hormonal root cause that most oil-control products miss. Most acne and oily-skin treatments focus on surface oil management or bacteria killing without understanding that excessive sebum production is often hormonally driven. Zinc PCA works differently: it inhibits 5-alpha-reductase, the enzyme that converts testosterone into DHT (dihydroxytestosterone). DHT stimulates sebaceous gland activity and increases sebum production — this is why hormonal acne and oily skin worsen during puberty, menstrual cycles, and periods of hormonal stress. By blocking this conversion, Zinc PCA reduces sebum production at the hormonal level, not just on the surface. This makes it particularly powerful for clients with persistent acne, seborrhoea, or hormonally-driven oiliness that conventional treatments fail to control. Beyond sebum regulation, Zinc PCA provides anti-inflammatory benefits that reduce redness and swelling characteristic of acne and rosacea, whilst antibacterial properties inhibit acne-causing bacteria. The critical insight is that acne and oily skin are often dehydrated — the skin overproduces sebum to compensate for barrier dysfunction. XS hyaluronic acid addresses this by providing comprehensive hydration that actually improves barrier function and reduces sebum overproduction. The fruit acid blend provides gentle micro-exfoliation that removes dead cells and opens congested pores without harsh irritation. For clients frustrated by stubborn oiliness, hormonal acne, or rosacea that won't respond to conventional treatments, this is the serum that addresses root causes. For Mixlab system users, this is the sebum-regulation and anti-inflammatory foundation to mix with targeted actives for fully personalised formulations.

What it targets

Excessive sebum and oily skin

Acne and blemishes

Hormonal acne and seborrhoea

Rosacea and inflammation

Open pores and enlarged pore appearance

Bacteria overgrowth and congestion

Uneven skin texture

Suits

  • Oily & seborrhoea-prone skin
  • Acne-prone & inflamed skin
  • Rosacea & couperosis skin
  • Combination & congested skin

Key ingredients

What's inside, and why.

  • Zinc PCA (Sebum Regulator)
    01

    Zinc PCA (Sebum Regulator)

    A clinically active zinc complex that inhibits 5-alpha-reductase, the enzyme converting testosterone to DHT. Reduces sebum production at the hormonal level, provides anti-inflammatory and antibacterial benefits, and serves as a powerful antioxidant. Essential for oily skin, acne, seborrhoea, and rosacea control.

  • Sodium Hyaluronate (XS — Low Molecular Weight)
    02

    Sodium Hyaluronate (XS — Low Molecular Weight)

    An advanced humectant with extra-small molecular weight for deep dermal penetration combined with larger weights for surface hydration. Provides comprehensive moisture binding at all skin layers, supporting barrier function and sebum regulation during acne treatment.

  • Lactic Acid (Fruit Acid Blend Component)
    03

    Lactic Acid (Fruit Acid Blend Component)

    A naturally-derived alpha-hydroxy acid that provides gentle micro-exfoliation whilst improving skin's natural moisture factor. Removes dead skin cells that contribute to pore congestion and acne, whilst supporting pH balance and gentle renewal.

  • Citric Acid (Fruit Acid Blend Component)
    04

    Citric Acid (Fruit Acid Blend Component)

    A fruit-derived hydroxy acid that supports pH balance and gentle exfoliation. Works synergistically with other fruit acids to activate skin's renewal enzymes and reduce the appearance of enlarged pores.

  • Propanediol
    05

    Propanediol

    A natural humectant and preservative booster that enhances skin hydration and formula stability. Supports the hydrating infrastructure whilst maintaining the lightweight, absorbing texture essential for oily and acne-prone skin.

What I'd pair it with

Complete your routine.

Skincare works best as a routine, not a single product. These are the products I'd use alongside it.

Buy any 3 or more HydroPeptide, IMAGE or Ekseption products together and save 20%. Applied automatically at checkout.

The full routine Save 20% $234.72 $293.40 Hyaluronic ZnPCA plus 3 pairings. Includes your 20% routine saving of $58.68. Ships free.
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  • HydropeptideSolar Defense Tinted Face GuardSPF protection, hydration, and a natural glow. All in one step.$85.00 · 50ml
  • EkseptionEnzyme Powder Cleanse & PeelEnzyme powder cleanser that transforms to silky foam. Gentle exfoliation with Papain enzyme for all skin types.$57.50 · 45g
View cart →
The full routine Save 20% $234.72 $293.40 Hyaluronic ZnPCA plus 3 pairings. Includes your 20% routine saving of $58.68. Ships free.

Before you buy

Your questions, answered by your NP.

Everything people usually ask me before choosing this product.

Still unsure? Ask me →
What makes this different from other oil-control serums?

Most oil-control serums focus on surface oil management or bacteria killing without addressing the hormonal root cause of sebum overproduction. Mixlab Hyaluronic ZnPCA is fundamentally different because Zinc PCA inhibits 5-alpha-reductase, the enzyme that converts testosterone into DHT (dihydroxytestosterone). DHT stimulates sebaceous gland activity and increases sebum production — this is why hormonal acne and oiliness worsen during puberty, menstrual cycles, and hormonal stress. By blocking this conversion, Zinc PCA reduces sebum production at the hormonal signalling level, not just on the surface. This makes it especially powerful for hormonal acne, seborrhoea, and persistent oiliness that conventional treatments fail to control. Beyond sebum regulation, Zinc PCA provides anti-inflammatory benefits that reduce acne and rosacea redness, whilst antibacterial properties inhibit acne bacteria. The critical insight is that acne and oily skin are often dehydrated — the skin overproduces sebum to compensate for barrier dysfunction. XS hyaluronic acid provides comprehensive hydration that actually improves barrier function and reduces compensatory sebum overproduction. Most oil-control serums dry skin out; this one hydrates whilst regulating oil. This is hormonal sebum regulation, not temporary oil management.

Is it suitable for sensitive skin?

Yes — Zinc PCA is exceptionally well-tolerated by all skin types, including sensitive and reactive skin. The anti-inflammatory properties actually reduce reactivity. The fruit acid blend is gentler than conventional acne exfoliants. The hyaluronic acid provides protective hydration. For sensitive, oily, or reactive skin, use morning and evening consistently — the gentle mechanism means you get sebum control and anti-inflammatory benefits without irritation. Clients with reactive oily skin often report that Zinc PCA improves overall skin resilience and reduces inflammation-driven breakouts.

Where does this fit in my routine?

This is your sebum-regulating and anti-inflammatory serum step, used morning and evening as foundational infrastructure. Morning routine: cleanse → apply Hyaluronic ZnPCA to clean skin → allow to absorb fully (2–3 minutes) → apply other serums or treatments if using → apply lightweight moisturiser → SPF 50+. Evening routine: cleanse → apply Hyaluronic ZnPCA → allow to absorb → apply other treatments or lightweight night cream if desired. Hyaluronic ZnPCA is the foundation oil-control and anti-acne step for oily and acne-prone skin. For Mixlab system users, this is the sebum-regulation base layer to which personalised serums are added — apply this first (allow to absorb), then layer other Mixlab serums on top according to individual needs.

How do I use it?

Clean skin prior to application. Apply a few drops to the skin morning and evening. Gently pat or press (do not drag) the serum into the skin, allowing it to absorb fully (2–3 minutes). A moisturiser can be applied over the top (even oily skin benefits from lightweight hydration). Always apply SPF 50+ during the daytime. For Mixlab blending: apply Hyaluronic ZnPCA as the sebum-regulation and anti-inflammatory layer, then layer other Mixlab serums on top according to personalised protocol, allowing each to absorb before applying the next. Once opened, use within 6 months.

When will I see results?

Immediate results on first use — skin feels less oily, more comfortable, and less inflamed from Zinc PCA's anti-inflammatory effects. Cumulative visible results compound over 1–3 weeks: sebum production visibly decreases, breakouts reduce in frequency and severity, redness and inflammation diminish, pore size appears smaller, and overall skin clarity improves. Unlike harsh acne treatments that cause irritation and dryness, Hyaluronic ZnPCA delivers results without disruption. Clients report noticeable oil reduction and breakout decrease within 1–2 weeks, with significant improvement in acne control, inflammation, and pore appearance by 3–4 weeks. Hormonal sebum regulation continues progressing over 6–8 weeks as the 5-alpha-reductase inhibition effect accumulates.

Can I use it during pregnancy or breastfeeding?

Yes — Mixlab Hyaluronic ZnPCA is a topical serum with no systemic actives, making it safe during pregnancy and breastfeeding. Zinc PCA is not systemically absorbed. Hormonal acne commonly worsens during pregnancy, so this sebum-regulating and anti-inflammatory serum is especially valuable for pregnant clients. The gentle, anti-inflammatory approach is ideal during this sensitive period. The sebum-regulating benefits help counteract hormonal acne changes during pregnancy and postpartum.

Can I use it with other acne treatments, or should it be standalone?

Both. As a standalone serum, it delivers comprehensive sebum-regulating and anti-acne benefits and is perfect for clients seeking core oil control without harsh treatments. As part of a routine with other serums: apply Hyaluronic ZnPCA first (as the sebum-regulation and anti-inflammatory foundation), allow it to absorb (2–3 minutes), then layer other serums on top. The Zinc PCA and hyaluronic acid infrastructure allows other actives to work optimally without irritating acne-prone skin. For Mixlab system users specifically, Hyaluronic ZnPCA is designed to be mixed with other Mixlab serums to create fully customised formulations — you can blend this with microbiome-balancing, brightening, or exfoliating serums to create personalised, targeted formulations tailored to individual acne, oiliness, and skin concerns, all with sebum-regulation foundation.

How long does a 70ml bottle last?

At twice-daily application (morning and evening, a few drops), a 70ml bottle lasts approximately 6–8 weeks. The lightweight serum formulation means a small amount covers the entire face and neck effectively — you need less product than heavier acne creams. The generous 70ml size provides excellent value and longevity for daily oil control use. Once opened, use within 6 months.

Is $45.95 worth it for an oil-control serum?

The value case is multifaceted and evidence-based. Most acne and oil-control treatments cost similar amounts but come with harsh side effects (irritation, drying, barrier damage) that worsen long-term skin health. Mixlab Hyaluronic ZnPCA is premium-priced because Zinc PCA is clinically documented to regulate sebum production at the hormonal level through 5-alpha-reductase inhibition — this addresses the root cause of hormonal acne and seborrhoea, not just surface symptoms. This is not a temporary oil-control treatment; it's a hormonal sebum-regulation system. Over 6–8 weeks of consistent daily use, you're seeing measurable sebum reduction, acne control, inflammation decrease, and pore minimisation — without irritation or tolerance-building. The anti-inflammatory and antibacterial benefits provide additional acne-fighting mechanisms. For clients struggling with hormonal acne, stubborn oiliness, seborrhoea, or rosacea, this is the investment that addresses root causes. For Mixlab system users, this becomes the sebum-regulation foundation to which personalised actives are added. The documented hormonal sebum-regulating efficacy justifies the investment entirely.

What's in it? (full ingredient list)

Aqua (Water), Sodium Hyaluronate, Zinc PCA, Lactic Acid, Propanediol, Citric Acid, Tartaric Acid, Gluconic Acid, Polysorbate 80, Parfum, Citral, Limonene, Geraniol

Please check the ingredient list on the packaging before use.